In a universe whose size is beyond human imagining, where our world floats like a dust mote in the void of night, men have grown inconceivably lonely. We scan the time scale and the mechanisms of life itself for portents and signs of the invisible. As the only thinking mammals on the planet--perhaps the only thinking animals in the entire sidereal universe--the burden of consciousness has grown heavy upon us. We watch the stars, but the signs are uncertain. We uncover the bones of the past and seek for our origins. There is a path there, but it appears to wander. The vagaries of the road may have a meaning, however; it is thus we torture ourselves.
Lights come and go in the night sky. Men, troubled at last by the things they build, may toss in their sleep and dream bad dreams, or lie awake while the meteors whisper greenly overhead. But nowhere in all space or on a thousand worlds will there be men to share our loneliness. There may be wisdom; there may be power; somewhere across space great instruments, handled by strange, manipulative organs, may stare vainly at our floating cloud wrack, their owners yearning as we yearn. Nevertheless, in the nature of life and in the principles of evolution we have had our answer. Of men elsewhere, and beyond, there will be none forever.
--Loren Eiseley, The Immense Journey